Prashanthi

Dr. Prashanthi K

Assistant Professor Grade — P2|Faculty of Life and Allied Health Sciences, Department of Biotechnology


Dr. K. Prashanthi has 12 years of teaching and research experience and is an Assistant Professor at the Department of Biotechnology, FLAHS, RUAS. Her research areas of interest include Host Pathogen interaction, Cancer metabolism and Dengue Host interaction. Dr. Prashanthi has degrees in BSc (Chemistry Hons) (1997) from Sri Sathya Sai Institute of Higher Learning, AP and MSc (Biochemistry) from Sri Krishnadevaraya University, AP. She acquired 97.71 percentile (All India 31 Rank) in GATE-99 and qualified the National Eligibility test (NET) for the Junior Research Fellowship (JRF) in 1999 conducted by Joint Council of Scientific & Industrial Research (CSIR) – University Grants Commission (UGC). She obtained her Doctor of Philosophy degree in Virology from Indian Institute of Science (IISc) in 2008. She did her post doc in the field of Systems biology of Host- MTB interaction @ IISc. She was also awarded the DBT- Research Associate fellowship during her post doc. She began teaching career as an Assistant Professor at Department of Biochemistry, Indian Academy Degree College – Autonomous, Bangalore (2014−2018) and eventually became the Head of the Department (2018−2020). She is an active member in the BoS of many Autonomous Colleges and Universities. She is the Hon. Secretary of the Indian Women Scientist Association, Bengaluru Branch and Executive Member of the Indian Society of Ethology, Bengaluru. She was the Co-ordinator for 2 Science Academies Lecture Workshops and a DBT Star College sponsored National Symposium.

Qualifications

  • PhD in Virology

    Indian Institute of Science, Karnataka

  • MSc Biochemistry

    Sri Krishnadevaraya University, AP

  • BSc Chemistry (Hons) with Botany and Zoology

    Sri Sathya Sai Institute of Higher Learning, AP

Experience

Total Years of Experience: 12 Years / 1 Month

Academic:

  1. Research Associate @ Prof. Nagasuma Chandra’s Lab, Department of Biochemistry, Indian Institute of Science : Oct 2008 – Jan 2014 (5 years, 3 months)
  2. Teaching:
    1. Assistant Professor, Department of Biotechnology, Faculty of Life and Allied Health Sciences, M S Ramaiah University of Applied Sciences : October 2020 – till date (4 months)
    2. Head and Assistant Professor, Department of Biochemistry, Indian Academy Degree College –Autonomous : July 2018 – September 2020 (2 year, 2 months)

Assistant Professor, Department of Biochemistry, Indian Academy Degree College –Autonomous : Feb 2014 – June 2018 (4 years, 4 months)

Training Experience


  • Genomics
  • Bioinformatics
  • Science Journalism
  • Quantitative Systems Biology


Research Interest

  • Host Pathogen Interaction
  • Dengue – Human Interaction
  • Bioinformatics
  • Cancer Metabolism

  • Hon. Secretary, Indian Women Scientists’ Association, Bengaluru Branch.
  • Executive member of Indian Society of Ethology, Bengaluru.
  • BoS Member for the BSc Biochemistry, Maharani Lakshmi Ammani College
  • BoS Member for the PhD Program, Garden City University.
    • Organizing Secretary for the DBT Sponsored Conference: Confluence 2015 – A Systems Biology Approach (April 24th – 25th, 2015), Indian Academy Degree College Autonomous
    • Co-ordinator for Science Academies’ Lecture Workshop: New Horizons in Chemical and Biochemical Sciences” held at Indian Academy Degree College Autonomous during 22nd – 23rd September 2016.
    • Co-ordinator for Science Academies’ Lecture Workshop: Cognitive and Behavioral Sciences” held at Indian Academy Degree College Autonomous during 4th – 5th October 2018.
    • Co-ordinator for DBT Star College sponsored National Symposium on Recent Advances at the Interface between Chemical & Biological Sciences” organized at Indian Academy Degree College, on 29th July 2019.
    • Co-ordinator of the workshop Molecular Docking Studies in Drug Discovery” organized on 7th May 2019 @ Indian Academy Degree College Autonomous.
    • Designed, Conducted and Executed a value addition course on Systems Biology” for the M. Sc. Life Sciences students.

  • Obtained 97.71 percentile (All India 31st Rank) in GATE-99.
  • Qualified in the National Eligibility test (NET) for the Junior Research Fellowship (JRF) in 1999 conducted by Joint Council of Scientific & Industrial Research (CSIR) – University Grants Commission (UGC).
  • DBT-RA @ Prof. Nagasuma Chandra Lab, Department of Biochemistry, Indian Institute of Science
  • DBT-Star College Coordinator @ Indian Academy Degree College – Autonomous (Jan 2018 – Sept 2020)

  • Ph.D. Dissertation:

  • Characterization of the High Level Expression Phenotype of the Cell Line PCX5 and Studies on the Regulation of Rotaviral Gene Expression in Mammalian Cells.

  • National Conference Papers

  • Christopher Bathula and Karyala Prashanthi. Dengue Virus – Human Protein Interactome, Proceedings of the National Conference: Confluence 2015 – A Systems Biology Approach, Pg 14, ISBN No. 978-81-920859-9-10.

  • National Journal Papers

  • Malathi Rajendran, Prashanthi K, Karthikeyan J. (2019) Molecular docking of fisetin as a multi-target drug in the treatment of Parkinson’s disease, Journal of Drug Delivery and Therapeutics. 2019; 9(1-s):1-4.

  • International Journal Papers

  • Karyala, Prashanthi and Namsa, Nima D and Chilakalapudi, Durga Rao (2010) Translational Up-Regulation and High-Level Protein Expression from Plasmid Vectors by mTOR Activation via Different Pathways in PC3 and 293T Cells. In: PLos One, 5 (12).

  • Mukherjee, S., Sambarey, A., Prashanthi, K. and Chandra, N. (2013), Current trends in modeling host–pathogen interactions. WIREs Data Mining Knowl Discov, 3: 109–128. doi: 10.1002/widm.1085

  • Awanti Sambarey, Karyala Prashanthi and Nagasuma Chandra. Mining large-scale response networks reveals ‘topmost activities’ in Mycobacterium tuberculosis infection. Scientific Reports, 3: 2302, DOI: 10.1038/srep02302.

  • Karyala P, Metri R, Bathula C, Yelamanchi SK, Sahoo L, et al. (2016) DenHunt - A Comprehensive Database of the Intricate Network of Dengue-Human Interactions. PLOS Neglected Tropical Diseases 10(9): e0004965. https://doi.org/10.1371/journal.pntd.0004965.

  • Rohith Kumar Guddeti, Prerna Bali, Prashanthi Karyala, Suresh B. Pakala, (2019) MTA1 coregulator regulates LDHA expression and function in breast cancer, Biochemical and Biophysical Research Communications, Volume 520, Issue 1, 54-59,ISSN 0006-291X.

  • Patel, A., Rajendran, M., Shah, A., Patel, H., Pakala, S. B., & Karyala, P. (2021). Virtual screening of curcumin and its analogs against the spike surface glycoprotein of SARS-CoV-2 and SARS-CoV. Journal of biomolecular structure & dynamics, 1–9. https://doi.org/10.1080/07391102.2020.1868338.

  • Rohith Kumar Guddeti, Liz Thomas, Anbarasu Kannan, Prashanthi Karyala, Suresh B. Pakala. MORC2 affects glucose metabolism by regulating the expression of LDHA through a feed forward loop with c-Myc. Accepted in FEBS Letters.

  • Book Chapter

  • Rhea Conchita Gonsalves, Himavani Pacharla, Sai Manohar, Siva Kumar Belliraj, Ekta Tripathi, Karyala Prashanthi, Suresh B. Pakala, 2021 ‘SARS-CoV2 – Host Cell Interactions and pathways : Understanding its Physiology, Pathology and Targeted Drug Therapy’, in Viswanath Buddolla (ed.), Pandemic Outbreaks in the Twenty-First Century, Academic Press. (accepted)

  • Prashanthi K., Chandra N. (2013) Host–Pathogen Interactions. In: Dubitzky W., Wolkenhauer O., Cho KH., Yokota H. (eds) Encyclopedia of Systems Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9863-7_91

  • Popular Article

  • Prashanthi Karyala and Sarita Kamat (2020) Online education in India — the good, the bad and the ugly!, published online in IndiaBioscience columns (https://indiabioscience.org/columns/education/online-education-in-india-the-good-the-bad-and-the-ugly) and COVID Gyan website published on 5th Oct 2020 (https://covid-gyan.in/article/online-education-india%E2%80%89%E2%80%94%E2%80%89-good-bad-and-ugly)