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Dr. Nishanth Ramdas
Assistant Professor
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School/College
Faculty of Pharmacy
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Department
Department of Pharmaceutical Chemistry
Dr. Nishanth Ramdas is an Assistant Professor in the Department of Pharmaceutical Chemistry at the Faculty of Pharmacy, Ramaiah University of Applied Sciences, Bengaluru, India.
He obtained his Ph.D. in Pharmaceutical Chemistry from VIT University and subsequently completed postdoctoral research at the University of Oxford, UK, under the Marie Skłodowska-Curie Actions (MSCA) programme. His research integrates synthetic organic chemistry, medicinal chemistry, and chemical biology, with a focus on the design and synthesis of biologically active small molecules for therapeutic applications.
Dr. Ramdas has authored numerous peer-reviewed publications and book chapters in leading international journals. His current research interests include targeted protein degradation (PROTACs), medicinal chemistry, heterocyclic chemistry, sustainable synthetic methodologies, and the discovery of novel therapeutic agents for cancer and infectious diseases.
Passionate about teaching and mentoring, he is committed to fostering scientific curiosity, research excellence, and innovation among students while developing collaborative research that bridges fundamental chemistry with translational drug discovery.
Qualifications
- Ph.D.
Vellore Institute of Technology , 2021
- M.Pharmacy
Manipal University , 2015
- B.Pharmacy
JNTU-H , 2013
- Targeted Protein Degradation (PROTACs and Molecular Glues), Anti tubercular drug discovery, Green and sustainable organic synthesis, Microwave assisted and sonication supported organic synthesis, Insilico drug design and AI assisted drug design.
- Rao, R.N., Maiti, B. and Chanda, K. (2020) 'Organic synthesis on ionic liquid support: A new strategy for the liquid-phase organic synthesis (LPOS)', in Organic Synthesis Using Ionic Liquids. Elsevier, pp. 49–104.
- Rao, R.N., Maiti, B. and Chanda, K. (2020) 'Organic synthesis on ionic liquid support: A new strategy for the liquid-phase organic synthesis (LPOS)', in Organic Synthesis Using Ionic Liquids. Elsevier, pp. 49–104.
- Member of Royal Society of Chemistry (MRSC)-2024
- Marie Curie Postdoctoral Fellow (2022)
- ICMR-Senior Research Fellow (2019)
- Peer reviewer for MDPI and Taylor & Francis journals.
International Journal Papers
- Rao, R.N., Soumyadip, D., Kezia, J., Mohammed, M.A., Balamurali, M.M. and Chanda, K. (2024) 'Synthetic access to diverse thiazetidines via a one-pot microwave-assisted telescopic approach and their interaction with biomolecules', Organic & Biomolecular Chemistry, 22, pp. 3249–3261.
- Sharda, S., Rao, R.N., Harshavardhan, B., Rebecca, K.E., Trinath, J., Raghavender, M., Sharmistha, B., Varadaraj, B.G., Gautham, G.S., Srinivas, O., Parimal, M. and Manojit, P. (2023) 'Wang resin catalysed sonochemical synthesis of pyrazolo[4,3-d]pyrimidinones and 2,3-dihydroquinazolin-4(1H)-ones: Identification of chorismate mutase inhibitors having effects on Mycobacterium tuberculosis cell viability', Bioorganic Chemistry, 134, 106452.
- Rao, R.N. and Chanda, K. (2022) '2-Aminopyridine: An unsung hero in drug discovery', Chemical Communications, 58, pp. 343–382.
- Panchangam, R.L., Rao, R.N., Balamurali, M.M., Hingamire, T.B., Shanmugam, D., Manickam, V. and Chanda, K. (2021) 'Antitumor effects of Ir(III)-2H-indazole complexes for triple-negative breast cancer', Inorganic Chemistry, 60, pp. 17593–17607.
- Roniboss, A., Rao, R.N., Balamurali, M.M. and Chanda, K. (2021) 'Hydrazide-derived colorimetric sensor for selective detection of cyanide ions', Inorganic Chemistry Communications, 134, 108965.
- Rao, R.N., Jena, S., Mukherjee, M., Maiti, B. and Chanda, K. (2021) 'Green synthesis of biologically active heterocycles of medicinal importance: A review', Environmental Chemistry Letters.
- Rao, R.N. and Chanda, K. (2021) 'An expeditious microwave-assisted one-pot sequential route to pyrido-fused imidazo[4,5-c]quinolines in green media', New Journal of Chemistry, 45, pp. 3280–3289.
- Rao, R.N., Panchangam, R.L., Manickam, V., Balamurali, M.M. and Chanda, K. (2020) 'Synthesis and antitumor activity evaluation of cyclometalated 2H-indazole ruthenium(II) and iridium(III) complexes', ChemPlusChem, 85, pp. 1800–1812.
- Rao, R.N. and Chanda, K. (2020) 'An assessment study of known pyrazolopyrimidines: Chemical methodology and cellular activity', Bioorganic Chemistry, 99, 103801.
- Saikia, A.A., Rao, R.N., Maiti, B., Balamurali, M.M. and Chanda, K. (2020) 'Diversity-oriented synthesis of thiazolidine-2-imines via microwave-assisted one-pot telescopic approach and its interaction with biomacromolecules', ACS Combinatorial Science, 22, pp. 630–640.
- Saikia, A.A., Rao, R.N., Das, S., Jena, S., Rej, S., Maiti, B. and Chanda, K. (2020) 'Sequencing [3+2]-cycloaddition and multicomponent reactions: A regioselective microwave-assisted synthesis of 1,4-disubstituted 1,2,3-triazoles using ionic liquid-supported Cu(II) precatalysts in methanol', Tetrahedron Letters, 61, 152273.
- Roniboss, A., Shrinivas, M., Rao, R.N., Balamurali, M.M. and Chanda, K. (2019) 'Environment-dependent photophysical and fluorescence turn-off sensing properties of Fe(III) by substituted phenyl isochromenopyrrol-5-ones', Photochemical & Photobiological Sciences, 18, pp. 2977–2988.
- Rao, R.N., Balamurali, M.M., Maiti, B., Thakuria, R. and Chanda, K. (2018) 'Efficient access to imidazo[1,2-a]pyridines/pyrazines/pyrimidines via catalyst-free annulation reaction under microwave irradiation in green solvent', ACS Combinatorial Science, 20, pp. 164–171.
- Meena, D.R., Rao, R.N., Maiti, B. and Chanda, K. (2017) 'Novel Cu(I)-catalyzed one-pot multicomponent synthesis of the antiepileptic drug rufinamide', Research on Chemical Intermediates, 43, pp. 4711–4717.
- Rao, R.N., Maiti, B. and Chanda, K. (2017) 'Application of Pictet–Spengler reaction to indole-based alkaloids containing tetrahydro-β-carboline scaffold in combinatorial chemistry', ACS Combinatorial Science, 19, pp. 199–228.
- Member of Royal Society of Chemistry (MRSC)
- Member of American Chemical Society.
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