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Oral & Maxillofacial Pathology and Oral Microbiology

Oral Cancer Research Center

Since its inception in 2015, OCRC has accelerated research in the field of oral cancer and precancer.

The centre comprising of Oral Pathologists work in the field of pathogenesis and molecular diagnostics, the team focusses to establish translational oncology research platform with a multidisciplinary approach resulting quality research outcomes.

Work is channelized in collaboration with Oral and Maxillofacial Surgery, Oral Medicine & Radiology, Public Health Dentistry and Life Sciences focusing on surgical management and therapeutic procedures.

ocrc cancer
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Oral Cancer

Oral squamous cell carcinoma (OSCC) is the third most common cancer in India and the major risk factors are widely known. Even with the provision of advanced treatment modalities, the morbidity and mortality rates still remain high in India.

The low-income groups in India are affected most due to a wide exposure to risk factors such as tobacco chewing and insufficient exposure to newly diagnostic aids, resulting in a delay in reporting of oral cancer. OSCC patients have high potential for invasiveness through regional lymph node metastasis and recurrence. Exact reasons for recurrence and metastasis are yet unclear. Several factors may contribute to treatment failure, and our primary interest relates understanding the biological behaviour of OSCC at molecular and cellular levels

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Verticals Of OCRC

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Centre of Excellence – Cancer Biorepository

About

A biorepository or biobank is a center that collects, processes, stores, and distributes biological materials to help support research teams and other professionals in future scientific investigations. The OCRC biorepository helps to manage and contain biospecimens from humans.

Scope

The main purpose or function of the biorepository is to retain biospecimens and their associated data for research purposes. They will ensure and manage the quality, accessibility, disposition, and distribution of all the specimens.

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Artificial Intelligence & Machine Learning

About

AI refers to the ability of a machine to perform tasks commonly associated with intelligent human behavior. Including disciplines from both computer science and mathematics. Applications of AI in healthcare include improvement of disease diagnosis and the development of effective therapies

Scope

The significant amount of data generated from cancer patients and theoru tisseu can be used to improve oncologic care. AI and ML can alter disgnostic outcomes, treatment regimes, correction of pitfalls, and future directions in oncology

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Molecular Research

About

Molecular research includes genomics and metagenomics. Metagenomics is the study of genetic material recovered directly from environmental samples. Genomics invloves study of structure, function, evolution and mapping of genome

Scope

The scope is to monitor disease burden and recurrence. It facilitates prognostic and therapeutic decisions. Genomics enables quick screening of diseases and their diagnosis. It gives an overall view of disease susceptibility

Sowmya SV

Research Centre Head

Professor and HOD, Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, MSR Nagar, Bengaluru-560054, Karnataka, India.

Department of Oral Pathology & Microbiology, Room no 9, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, Gnanagangothri Campus, New BEL Road, M S R Nagar, Bangalore, Karnataka, INDIA - 560 054.

Dr. Sowmya SV,

Phone: +91 9945784509

E-mail: drsowmya25@gmail.com

Our Vision

To establish Translational Oncology Research Platform with a multidisciplinary approach

Our Mission

To advance knowledge in oral cancer through
quality research to impact the society

Research Goals

  • Maintain an extensive Oral Cancer Database & establish a Biobank with high quality & integrity of specimens through ethical transparency to advance the cancer research
  • Accelerate cancer research to develop diagnostic markers for early detection, prognostic and predictive tools and therapies
  • Promote the development of new drugs, devices, and other medical interventions
  • Create unique training opportunities for budding scientists ( PGs, Doc, Post-doc’s ) and encourage new talent to explore basic science research
  • Explore the possibilities to collaborate/MOU with Reputed Private labs, Institutions, Hospitals @National and International levels
  • Gain access to new funding streams to support both institutional and individual projects
  • To drive quality research publications in impact factor journals

Proposed Research work

  • To pursue multidisciplinary clinical and applied research on oral cancer to address the current challenges from local and global perspectives for providing an affordable treatment modality
  • To explore and adopt validated advanced diagnostic tools at a molecular level to analyse, detect and prevent oral cancer
  • To investigate the genetic basis of susceptibility of individuals to oral cancer
  • To analyse the characteristics of specific genetic markers to establish the relationship between the cause, course and progress of oral cancer
  • To apply the evolving concepts of Pathogenesis and Molecular Diagnostics to research on oral cancer
  • To disseminate knowledge on concepts and practices of clinical research and treatment modalities in oral cancer
  • To develop and pursue joint initiatives for collaboration and partnership with Universities, Research Centres and Industries to offer solution to detect and prevent oral cancer

Rationale for establishing Oral cancer centre in Bangalore

  • Bangalore, a hub for corporate hospitals and educational institutions are more inclined towards surgical and palliative care than preventive measures.
  • Such measures can be aided by a ‘Cancer research facility’. But research having taken the back seat has hindered its translation into clinical application.
  • Reputed Cancer Centres like Kidwai Memorial Institute of Oncology (KMIO), Health Care Global (HCG) Mazumdar-Shaw Cancer Center (MSCC) provide comprehensive care under one roof while our focus would be exclusive oral cancer research.
  • A disruptive transformation required, directs us to take a giant leap towards research as it has been revitalised by advanced technologies to isolate and characterise genomics, proteomics and other biomarkers that correlate with cancer.
  • The challenge now is to discover and develop markers for early cancer detection, overcome the inherent risk of over-diagnosis and the challenge of cost-effectiveness.
  • Also, the current scenario in professional courses reflect super saturation of ventures stagnating the researchers’ growth.
  • Our setup would empower the youth and provide a platform for research.
  • Having ICMR and NCRP units at Bangalore is an added advantage to our research centre to promote the cause of cancer research through collaboration.
  • Having collaborated with “Genotypic laboratory”, We feel appropriate to establish “The oral cancer research Centre “at MSRUAS.

Rationale for establishing cancer centre in MSRUAS

  • Dental practitioners, although skilled to detect precancerous and cancerous lesions, are accustomed to basic diagnostic tools and lack exposure to advanced technologies to foster research
  • Traditionally, oral cancer diagnosis and management has been limited to specific disciplines proving itself ineffective because of multifactorial etiology
  • In the recent years, there has been an increasing trend w.r.t. oral potentially malignant disorders and oral cancer patients at FDS, MSRUAS
  • Also, tobacco, alcohol de-addiction centre at FDS, MSRUAS, has caught its momentum for high-risk individuals
  • To provide a solution; OCRC will aim to create
  • A partnership providing a framework for oral cancer research via pooling and sharing of limited resources is intended
  • An oral cancer registry and integrate the information into national health surveillance systems
  • A conducive environment to train and develop the scientists of the future and to recruit and train world class researchers
  • A multidisciplinary approach for extensive and longitudinal research programmes

Thus, MSRUAS, intends a new model where academicians, clinicians and scientists will predominate research efforts towards the aim of building national research forum

Facility Creation

  • Penta head Microscope
  • Polarizing Microscopy
  • Blood Investigations
  • Photomicrography (photograph or digital image taken through a microscope
  • Bright field Microscopy
  • Image Analysis Software
  • Histopathology
  • Phase contrast Microscopy
  • Camera for Photomicrography
  • Cytopathology
  • Dark field Microscopy
  • Stereomicroscopy
  • Immunohistochemistry Laboratory
facaility creation

Prominent Visitors

peter_reichart

Prof. Dr. Peter Reichart

Chairman, Department of Oral Surgery &
Dental Radiology, University of Berlin, Germany

cheong

Prof. Dr. Cheong Sok Ching

Department of Oral & Maxillofacial Surgery,
Faculty of Dentistry, University of Malaya

saman

Prof. Dr. Saman Warnakulasuriya

Department of Oral Medicine,
King’s College, London

rosnah

Prof. Dr. Rosnah Binti Mohd Zain

Dean of Faculty of Dentistry,
University of Malaya

lakshman

Prof. Dr. Lakshman Samaranayake

Dean, Faculty of Dentistry, University of
Hong Kong

ross

Prof. Dr. Ross Kerr

Department of Oral & Maxillofacial pathology, Radiology & Medicine, New York University
College of Dentistry

StudyProgrammes Offered

Admission 2024

ADDRESS

New BEL Road, MSR Nagar , Bangalore - 560054