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Ramaiah University of Applied Sciences

Dr Mahesh

Dr. A R Mahesh

Assistant Professor

Dr. AR Mahesh is currently working as an Assistant Professor at Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ramaiah University of Applied Sciences, Bangalore. He has 9+ years of teaching experience, He graduated B. Pharm in Dayananda Sagar College of Pharmacy M. Pharm Pharmaceutical Chemistry from RGUHS, Bengaluru, MBA in Pharma Business Management from ICFAI, Tripura, and PhD under RGUHS. His passion for research has driven up to acquire a 7 Lakh grant from RGUHS, Bengaluru as a Co-investigator for research work in the arena of synthetic chemistry of novel anticancer agents. As an intellectual asset, an outcome of his research works has been published in the Scopus/​Web of Science indexed National and International Journals (28 + scientific publications) and more than 4 book chapters. He was awarded Grade‑A for the Continuous education program conducted by IISc, Bengaluru and acquired a proficiency Skill in 1D and 2D NMR Spectroscopy and their applications in Structure Biology. He has expanded his interest to the current IT related application in drug design with cognisance on molecular modelling of new chemical entities. He is an invitee as a resource person on the lateral domains of pharmaceutical sciences such as IPR, Soft skill trainer for UG and PG Students in reputed institutes and designated as a trainer in Faculty Development Program sponsored by RGUHS & APTI, Bengaluru. On prospect of knowledge exchange and development, he is a Life member of Association of Pharmaceutical Teachers of India, Foundation for Health and Environment Research, International Society for Pharmacoeconomics and Outcomes Research & Karnataka State Pharmacy Council.

Qualifications

  • Ph.D in Pharmaceutical Chemistry

    Dayananda Sagar College of Pharmacy, Rajiv Gandhi University of Health Sciences, Bengaluru

  • M.B.A (Pharmaceutical Business Management)

    Institute of Chartered Financial Analysts of India

  • M. Pharm (Pharmaceutical Chemistry)

    Krupanidhi College of Pharmacy, Bengaluru

  • B. Pharm

    Dayananda Sagar College of Pharmacy, Bengaluru

Experience

Total Years of Experience: 10.98 Years 

Training Experience

  • Secured A – Grade in Proficiency course (1D and 2D NMR Spectroscopy: Applications in Structure Biology) in IISc, Bengaluru,Jan-May 2016
  • Completed one year ​“Internship programme” and dissertation project in Department of Phytochemistry research at Natural Remedies Pvt., Ltd., Bangalore.
  • Undergone compulsory multi departmental ​“Internship Programme” in Minto Eye Hospital, Government of Karnataka, Bangalore

  • Anticancer drug design and development
  • Artificial Intelligence based drug discovery
  • Computer Aided Drug Design

Ph.D. Dissertation:

  • Synthesis and Evaluation of Nitrogen Mustard Linked Aurones As Possible Alkylating Anticancer Agents

National Conference Papers

  • “Synthesis and Hydrolytic kinetic study of some Antihypertensive Co-Drugs” in 63rd IPC, Bangalore. 16th ‑18th December 2011.
  • “Neonatal Infections — A Review” in National Conference on ​“Advances in Pharmacy Practice”, NET College of Pharmacy, Raichur. 28th ‑29th Nov, 2013.
  • “Synthesis of Benzofuranone fused Nitrogen Mustards & Evaluation of its Antineoplastic Activity. 3rd International Conference on Academic and Industrial Innovations: Transtions in Pharmaceutical, Medical and Biosciences organized by Innovative Academic Sciences in association with Paramita Health Care Society and Society for Ethnopharmacology-India on 22 – 23rd Oct, 2018 at Kala Academy, Panjim, Goa, India.

International Conference Papers

  • “Synthesis of some Co-Drugs of Propranalol and other antihypertensive drug via Anhydride Bridge and their hydrolytic kinetic study” in Indo-US Symposium on ​“Frontiers in Medicinal Chemistry and Drug Discovery” April 21st ‑23rd 2011.
  • “Synthesis and Hydrolytic kinetic study of derived antihypertensive codrugs” 3rd International Pharmaceutical Conference on ​“Current status and future perspective in Pharmaceutical Sciences”, PESCP. 19th ‑20th August 2011.
  • “Simultaneous Estimation of Paracetamol and Zaltoprofen by HPTLC”, International Conference on Drug Development and Clinical Research: Current Scenario & Opportunities. (KRUPACON Pharma-2018), Bengaluru. 12th ‑13th Oct, 2018.
  • “Synthesis of 2-(2-(Bis(2‑chloroethyl)amino)ethoxy)benzylidene) benzofuran‑3(2H)-one derivatives on the basis of benzaldehydes and acetophenones for its cytotoxic activity”, UNESCO/UNITWIN Network Web Seminar-2020, August 6 – 7, 2020 organized by BLDE University, Vijayapura, Karnataka, India.
  • “Investigation of Mode of Action of certain isolated compounds Tephrosia species as Anti-Microbial Agents”, KrupaPharmaCon 2021 | 3rd Global Online Conference & Workshop on Drug Development 4.0: Emerging Technologies, Krupanidhi College of Pharmacy, Bengaluru, on 02 – 03 July 2021.
  • “In-silico Investigation of Mode of Action of certain isolated compounds Tephrosia species as Anti-Microbial Agents”, KrupaPharmaCon 2021 | 3rd Global Online Conference & Workshop on Drug Development 4.0: Emerging Technologies, Krupanidhi College of Pharmacy, Bengaluru, on 02 – 03 July 2021.

National & International Journal Papers

  • J. Josephine Leno Jenita, Jahnavi Kulkarni, Agasa Ramu Mahesh, Shanaz Banu, Seema S. Rathore, Manjula D. Exposition of Protein Kinase Targeted Nanoplatforms: An Extensive Review. Advances in Pharmacology and Pharmacy,2022, 10(2): 128 – 137.
  • Bincy Raj, AR Mahesh, Ramakrishna Prudhivi, Prashant Tiwari, Sheena Marin Thomas, Suma Varghese, Krishna Das, Soosamma John. Hepatoprotective And Antioxidant Activity of Ampelocissus Indica Against CCl4 Induced Hepatic Damage In Albino Rats. Journal of Cardiovascular Disease Research, 2021, 12(6) 407 – 414.
  • J. Josephine Leno Jenita, Seema S. Rathore,Konduru Rohini, Manjula D, Shanaz Banu, Mahesh AR, Wilson Barnabas, Development and Evaluation of Eudragit Floating Microspheres containing Ezetimibe, Journal of Cardiovascular Disease Research, 2021, 12(4) 984 – 995.
  • Sahana John, Agasa Ramu Mahesh, Antimicrobial Susceptibility Sensitivity Pattern in Positive Urine Culture for Urinary Tract Pathogens from Tertiary Care Hospital. Journal of Drug Delivery and Therapeutics. Vol 11, Issue 5, 2021.
  • J Josephine Leno Jenita, Mahesh AR, Wilson B and Reddy Prasad, ​“Design and Evaluation of Oral Based Site-Specific Targeting of Oxaliplatin to Colorectal Cancer”. Acta Scientific Pharmaceutical Sciences 4.10 (2020): 22 – 30.
  • Josephine, L. Jenita., T. Richa, S. S. Rathore, D. Manjula, B. Wilson, and A. R. Mahesh, ​“Formulation and optimization of albumin nanoparticles loaded ivabradine hydrochloride using response surface design”, Journal of Drug Delivery Science and Technology, vol. 63: Elsevier, pp. 102461, 2021.
  • Vimal, J. S., V. Murugan, and A. R. Mahesh, ​“Effect of Tephrosia tinctoria in Triton WR-1339 and High Cholesterol-Diet Induced Hyperlipidemic Rats”, International Journal of Pharmaceutical Research, vol. 13, issue 02: Advanced Scientific Research, pp. 3221 – 3235, 2021.
  • Vimal, J. S., V. Murugan, and A. R. Mahesh, ​“Antihyperlipidemic effect of Tephrosia villosa in acute and chronic hyperlipidemia rat models”, Journal of microbiology, biotechnology and food sciences: Faculty of Biotechnology and Food Sciences, pp. e4222-e4222, 2021.
  • Vimal John Samuel, Rashmi DV, Agasa Ramu Mahesh. Antidiabetic activity of Tephrosia tinctoria in alloxan induced Diabetic Rats: A Preliminary Study, Research Journal of Pharmacy and Technology. 2021; 14 (2).
  • Agasa Ramu Mahesh, Vedigounder Murugan. Synthesis of 2-(2-(2-(Bis(2- chloroethyl)amino)ethoxy)benzylidene)benzofuran‑3(2H)-one derivatives on basis of benzaldehydes and acetophenones for its cytotoxic activity, International Journal of Pharmaceutical Sciences and Research. 2021; 12 (3).
  • Agasa Ramu Mahesh, Vimal John Samuel, Sourav Bag, Pavan Kalyan BG. E‑Pharmacies: An Emerging Market in Indian Retail Pharmacy, An Indian Perspective, Research Journal of Pharmaceutical Sciences. 2020; 8 (1).
  • Agasa Ramu Mahesh, Vedigounder Murugan. Synthesis of 2-(Bis(2‑chloroethyl)amino)-N- (4-((3‑oxobenzofuran‑2(3H)-ylidene)methyl)phenyl)acetamide Derivatives on Basis of Benzaldehydes and Acetophenones As Possible Alkylating Anticancer Agents. American Journal of Pharmtech Research. 2020; 10(3): 125 – 124.
  • Vimal John Samuel, Komal Kulkarni, Agasa Ramu Mahesh, Drug Utilization Pattern of Cephalosporins in In-Patient Departments of Tertiary Care Hospital. Journal of Pharmaceutical Sciences and Research. 2019;11(6), 2398 – 2401.
  • KB Premakumari, AR Mahesh, V Murugan, V Ezhilarasan. Simultaneous estimation of paracetamol and zaltoprofen in pharmaceutical dosage form by HPTLC. Research Journal of Pharmaceutical Technology. 2019;12(5),2017 – 78.
  • Vimal John Samuel, Agasa Ramu Mahesh, Vedigounder Murugan, Phytochemical and pharmacological aspects of Tephrosia genus: A brief review. Journal of Applied Pharmaceutical Science, 2019; 9(03), 117 – 125.
  • Asal Tanhaei Saeid, Fereshteh Jaferi, AR Mahesh, Ali Alipour, Komal Kulkarni, A Retrospective, Observational Study Effect of Polypharmacy and Drug Interactions in Elderly Patients. Saudi Journal of Medical and Pharmaceutical Sciences, 2019; 5(2): 147 – 153.
  • Vimal John Samuel and AR Mahesh, In- Vitro Antioxidant Properties, Acute And Subacute Toxicity Studies Of Tephrosia Calophylla On Albino Wistar Rats. International Journal of Pharmaceutical Sciences and Research, 2019; 10(6): 1000-07.
  • Kalpana Divekar, Sushma KR, AR Mahesh, Selectivity of Plants and Microbial Reduction of Ketones. Sch. Acad. J. Pharm. Jan 2018;7(1):26 – 35.
  • V Murugan, Shrideep Bhattacharjee, AR Mahesh, Synthesis and characterization of N‑N- {Bis(2′-Chloroethylamino)- nitroso}-2-benzylidene-1-benzofuran derivatives as antileukemic agents. Am. J. Pharm Health Res, 2016;4(7).
  • Mahesh AR, Samuel Yamta Mshelia and Vimal John Samuel, Therapeutic activities of Aurone, An appositely active molecule‑A Review. World Journal of Pharmacy and Pharmaceutical Sciences. 2016: 5(7):668 – 82.
  • Mahesh AR, Murugan V, Synthesis of a biologically pertinent molecule, Aurone-An extensive review. European Journal of Biomedical & Pharmaceutical Sciences. 2016: 3(1):112 – 16
  • M Somashekhar, Naira Nayeem, Mahesh AR. Botanical study of four ficus species of family Moraceae: A Review. International Journal of Universal Pharmacy and Bio Sciences, 2013; 2(6):558 – 570.
  • Somashekhar M, Mahesh AR. Synthesis and antimicrobial activity of piperazine derivatives. Am.J.Pharm Tech. 2013; 3(4):640 – 648.
  • Somashekhar M, Mahesh AR, Basavaraj Sonnad. Synthesis and antimicrobial activity of of 4-(morpholin-4-yl) benzohydrazide derivatives. World Journal of Pharmacy and Pharmaceutical Sciences, 2013; 2(4):2011 – 2020.
  • Manish K, Mahesh AR, Somashekhar M. International Journal of Pharma Research and Review, 2013; 2(8).
  • Mahesh AR, Ranganath MK, Harish Kumar DR, Enrichment of Flavanoids from the methanolic Extract of Boerhaavia Diffusa Roots by Partitioning Technique. Research Journal of Chemical Sciences, 2013:3(1),43 – 47.
  • Hitesh HS, Mayukh B, Mahesh AR. Isolation and characterization of chemical constituents of aerial parts of Lantana Camara. 01 2012; 1(6):198 – 207.
  • AR Mahesh, Harish Kumar, K, Raviraj Anand Devkar. Detail Study on Boerhaavia Diffusa Plant for its Medicinal Importance‑A Review, Research Journal of Pharmaceutical Sciences. 2012; 1(1):28 – 36.

  • Academic Excellence Award, 2019, by Institute of Scholars, India
  • Excellence Teaching in Higher Education, DKIRF Achievement Awards-2020, by DK International Research Foundation, India
  • Best presentation award, RAKCOPS, RAKCOPS International e‑Conference on Drug Development, 2021, United Arab Emirates
  • Best Runner up poster presentation award, Krupacon.2021

  • Karnataka State Pharmacy Council, India since 28-Mar-2009

    Registered Pharmacist

  • Association of Pharmaceutical Teachers of India

    Life Member

  • Karnataka State Pharmacy Council

    Life Member

  • Institute of Scholars, MSME

    Life Member

  • Foundation for Health and Environment Research

    Life Member

  • ISPOR 2020-2021

    Annual Member

  • DK International Research Foundation 2020-2021

    Annual Member